What is process analytical technology (PAT)?
A primer on PAT — the FDA-driven framework for measuring chemistry where it happens, why pharmaceutical and chemical manufacturers adopt it, and the tools that make it practical.
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Evergreen technical primers on the methods, instruments, and data analysis behind modern process analytics.
A primer on PAT — the FDA-driven framework for measuring chemistry where it happens, why pharmaceutical and chemical manufacturers adopt it, and the tools that make it practical.
Both techniques measure chemical composition without sampling. The choice is rarely close once you map your process onto five questions: water, fluorescence, specificity, dynamic range, and probe access.
Spectra are not answers. The bridge between a 1,000-channel spectrum and a number you can act on is chemometrics — a small toolbox of multivariate methods, used the same way for forty years.